Tuesday, October 4, 2022
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New data on Bone Loss in Menopause — Higher Bones


Are you vulnerable to dropping as much as 20% of your bone within the years round menopause?  Ladies with accelerated bone loss – known as “quick losers” in a brand new examine – run a larger danger of creating osteoporosis and weaker bones than the common lady. The typical lady solely loses 8-10% of her bone mass throughout the three years round menopause.

This new examine exhibits there’s a straightforward technique to discover out in the event you’re a “quick loser” of bone so you possibly can take motion to cease it.

Discover out in the event you’re a “quick loser” of bone

Researchers centered on using the N-telopeptide crosslinks check — a urine check — to assist establish ladies most in danger for larger and sooner bone loss.  As you lose bone, fragments of sure bone proteins present up within the urine; these are known as N-telopeptides (NTx). A lady with extra NTx protein fragments in her urine is probably going present process extra fast bone loss, and thus at greater danger of extreme menopausal bone loss.

Within the examine, researchers regarded on the NTx bone breakdown ranges in some 500 early post-menopausal ladies who have been inside 1-2 years of getting their last interval. They discovered the next:

  • The upper the urinary NTx degree, the sooner the speed of bone loss throughout the menopausal transition. This is smart: a better charge of bone breakdown would probably translate into larger bone loss.
  • A urinary NTx degree above 65 nM BCE/mM Cr was discovered to establish quick bone losers pretty nicely. To place this into context, the common premenopausal NTx degree is 36 nM BCE/mM Cr, and I’ve typically discovered postmenopausal ladies with a 50 NTx degree to be dropping ½ to 1% of bone mass per yr.
  • The affiliation between early postmenopausal NTx and charge of bone loss was stronger on the backbone than on the hip. This once more is smart, as a result of the backbone is metabolically lively trabecular bone, which typically loses mass years earlier than the hip does.
  • Moreover, wanting backwards, it was discovered {that a} excessive urinary NTx in perimenopause was additionally related to a better charge of bone loss throughout the menopause transition.

menopause chart 3

Menopausal bone loss shouldn’t be unfold evenly over the 10-year transitional interval (5 years earlier than a girl’s final interval and 5 years after).  Most bone loss happens within the 3-year interval beginning 1 yr earlier than a girl’s final interval and ending 2 years after her final interval — often known as “trans menopause.”

What does this analysis imply for you?

Should you’re noticing signs of perimenopause, like irregular durations and sizzling flashes or in the event you underwent menopause not too long ago (inside a few years), a easy check of your urine NTx degree may also help you establish an inclination to extreme bone loss.

Should you’re experiencing extreme bone loss, you possibly can take steps to seek out out why this is perhaps so and proper the scenario. Once I work with particular person purchasers, that is precisely the form of work I do with them.

Extra data on the easy urine check might be present in my brief video and related handbook. It’s also possible to order this check on-line via our on-line inquiry system at our lab accomplice Evexia.

And since you possibly can’t actually know when the yr earlier than your final interval will happen till you even have skilled your final interval, it’s a good suggestion to get began instantly on a powerful Higher Bones Program on the first indicators of perimenopause.

 

Reference:

Shieh A, et al.  Urinary N-telopeptide and charge of bone loss over the menopause transition an early post-menopause. J Bone Miner Res. 2016;31(11):2057-2064.

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Dr. Susan BrownI’m Dr. Susan Brown. I’m a medical nutritionist, medical anthropologist, author, and motivational speaker. Be taught my time-tested 6 step pure strategy to bone well being in my on-line programs.



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